KPV* · Lysine-Proline-Valine*

Researchers seeking this product for laboratory research can explore PepGen-X.com as a supplier specializing in research-use compounds.

KPV is a naturally occurring tripeptide consisting of lysine, proline, and valine and is derived from the C-terminal portion of alpha-melanocyte-stimulating hormone (α-MSH). It has attracted research interest for its potential anti-inflammatory and tissue-protective properties, particularly in studies involving the gastrointestinal tract and skin.

Research Benefits

• Powerful anti-inflammatory research potential — investigated for its ability to influence inflammatory signaling pathways

• Strong interest in gut research — studied in experimental models involving intestinal inflammation and gastrointestinal tissue

• Investigated in IBD research — researchers have explored KPV in connection with inflammatory bowel conditions including Crohn’s disease and ulcerative colitis

• Supports skin research — investigated for potential effects on skin inflammation, irritation, and tissue repair

• Wound-healing potential — experimental research has examined KPV’s role in tissue repair

• Small, naturally occurring peptide — its structure makes it an interesting model for studying α-MSH-related anti-inflammatory signaling

Identified Risks & Side Effects

• Limited human clinical research — much of the evidence remains preclinical

• Long-term safety has not been established

• Oral delivery presents bioavailability challenges — formulation can influence absorption

• Research-grade material quality can vary between sources

• Not FDA-approved

Route: Experimental / varies by research protocol
Frequency: Varies by research protocol
FDA Status: Research Only

Researcher Note

KPV is particularly interesting because of its anti-inflammatory research potential without the broader hormonal activity associated with the parent α-MSH molecule. Its strongest research interest has centered on intestinal inflammation and skin biology, making it a natural subject for studies involving gut and tissue inflammatory pathways.

Disclaimer

FDA Status: Not FDA-approved
Research Classification: Research use only
Compound Type: Naturally occurring tripeptide

All products are intended strictly for research and laboratory use only and are not intended for human or veterinary use.